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ID : tm286809651


Recombinant Bromelain: A Novel Source on Anti-Cancer

This study observed the anti-cancer activity of recombinant bromelain produced by the DNA recombinant technology thus easing the purification steps. The in-vitro cytotoxicity assay was conducted on the recombinant bromelain treated and untreated breast cancer (MCR-7) and normal cell lines (Vero). Then the half maximal inhibitory concentration (IC50) on all samples were recorded. Commercial bromelain served as a control in this experiment. The IC50 for both enzymes are 0.29mg/mL and 0.27mg/mL for recombinant and commercial bromelain respectively. Based on the IC50 values, both recombinant and commercial bromelain, did affect the cell lines at high concentration which is more than 0.25 mg/mL. zthe IC50 obtained from MCF-7 cells treated with recombinant and commercial bromelain are 0.20mg/mL and 0.16mg/mL respectively. Therefore, recombinant bromelain behaves similarly to the commercial bromelain in their anti-cancer activity especially to the MCF-7 breast cancer and Vero cells lines.

Kuala Lumpur Kuala Lumpur

ID : tm286899660


iHand

Sanitiser tangan yang diformulasikan dalam
bentuk cecair untuk memudahkan penggunaan
pada mana-mana permukaan termasuklah pada
sarung tangan getah yang terpakai di tangan.
Diperbuat menggunakan bahan-bahan dan
alatan pemprosesan yang patuh syariah

Kuala Lumpur Kuala Lumpur

ID : tm286909661


iGesic

iGesic efektif untuk melegakan pelbagai
kesakitan seperti sakit otot dan sendi di pelbagai
bahagian badan (lutut, leher, perut, pinggang dan
lain-lain lagi). Ia juga berkesan melegakan sakit
kepala. iGesic mengandungi 5 kombinasi bahan
aktif yang terdiri dari ubatan semasa iaitu methyl
salicylate, menthol, camphor dan minyak
peppermin sintetik, dan dari ubatan alami iaitu
minyak Eucalyptus

Kuala Lumpur Kuala Lumpur

ID : tm287329703


Effect Of Papain From Epicarp Extracts On Wound Healing And During Pregnancy

The present invention relates to an effect of Epicarp extract on wound healing and during pregnancy and more particularly the present invention relates to an effect of papain Epicarp extract on wound healing and during pregnancy.

Kuala Lumpur Kuala Lumpur

ID : tm287429713


An Acrylic Die For Hipbone Joint Casting

The present invention relates to a new design and development to a hipbone joint casting and more particularly the present invention relates to the use of an acrylic die for hipbone joint casting.

Kuala Lumpur Kuala Lumpur

ID : tm287569727


Novel Myco-Coagulant for Reducing Turbidity from River Water

Inventive steps filamentous fungi-inoculum preparation-shake flask fermentation-centrifugation-product (Myco-Coagulant)- application on Kaolin and actual river water.

Kuala Lumpur Kuala Lumpur

ID : tm287579728


Nanocellulose from Sugarcane Bagasse

The extraction of microfibrillated with minimal amount of chemicals and shortage time (about 10 hours) compared to other methods. The extracted MFC has Dia. (20-60nm) & length of several micrometers. It exhibits high crystallinity, lightweight, high strength, renewable nanomental.

Kuala Lumpur Kuala Lumpur

ID : tm289519922


Tissue-engineered Articular Cartilage

A method of producing a tissue-engineered articular cartilage is invented by applying a composition comprising articular cells and a biomaterial, plasma derivative fibrin with CaCl2. In the preferred embodiment, the human chondrocytes are cultured from a sample of patients knee joint mixed with human plasma derivative fibrin. This tissue-engineered articular cartilage is very useful for knee joint cartilage repair purposes or any other similar usages

Cheras Kuala Lumpur

ID : tm289529923


HIREPS- An Integrated Resuscitation Pendent and System

The present invention relates to an integrated resuscitation pendant system suspended from the ceiling of a medical room. The said pendant assembly comprises a first vertical arm, a first horizontal arm, a second vertical arm, a first housing means, a second housing means, a third housing means and a shelf frame structure. Optionally the said arms could further comprise at least one telescopic arm each, which could further include motorized means to pivotally rotate the arms and wherein when assembled, a plurality of medical accessories are attached for medical use. Optionally, the pendant assembly could further include more than one pendant assembly interconnected to one another and capable of operating independently from one another

Cheras Kuala Lumpur

ID : tm289549925


Composition of Palm Vitamin E as a Bone Strengthening Agent to a Prevent Fractures and Promote Fracture Healing

The present invention relates to composition of palm vitamin E as a bone strengthening agent, to prevent fractures and to promote fracture healing in normal or diseased bone. Specifically, this invention relates to the use of the palm vitamin E composition. Palm vitamin E composition comprising of tocotrienol-enhanced fraction consisting of 50-100% alpha, gamma and delta tocotrienol mixture.

Cheras Kuala Lumpur

ID : tm289569927


Polyethylene Scaffold for Cartilage Reconstruction

This invention provides a composition and method for the reconstruction of various shape of cartilages by using high density polyethylene as the endoskeleton material to provide predetermine, permanent shape and size of the cartilage graft.

This invention provides a composition and method for the reconstruction of various shape of cartilages by using high density polyethylene as the endoskeleton material to provide a predetermine, permanent shape and size of the cartilage graft. In the preferred embodiment, the cultured human chondrocytes is admixed with autologous plasma derivative fibrin to form an admixture and polymerizing the admixture to obtain a three-dimensional neocartilage sheet. This was followed by covering the neocartilage sheet onto the surface of high density polyethylene which has been trimmed into a desired shape. The formed autograft is then can be used for implantation. The tissue-engineered cartilage in the present invention is very useful for head and neck reconstructive surgeries.

Kuala Lumpur Kuala Lumpur

ID : tm289579928


Palm Oil-Based Parenteral Lipid Emulsion

A prototype palm oil-based nanoemulsion (ProNEMS) has been successfully produced by our research team using a modified emulsion processing procedure. Characterisation studies showed that palm oil has similar fatty acid contents (examples are linoleic, linolenic, oleic, and palmitic acids) as found in the soya bean, and olive oil emulsions used clinically (such as in parenteral or intravenous nutrition therapy).
Encouraging results are expected as palm oil is found to be good for health. Furthermore, ProNEMS is prepared using similar homogenising agent and excipients as those found in the production of the other parenteral lipid emulsions. Also, the preparation of ProNEMS is based on a standard pharmaceutical processing method. Lipid emulsion provides energy, and also essential fatty acids in parenteral nutrition therapy. It is hoped that ProNEMS can be an alternative in the use of lipid emulsion in parenteral nutrition therapy. ProNEMS can also be used as drug carriers.

Kuala Lumpur Kuala Lumpur

ID : tm289589929


Method of Construction Cartilage in Shape of Organ via Tissue Engineering

The invention relates to the formation of human cartilage in the shape of the trachea using human nasal septum chondrocytes mixed with biomaterial Pluronic F127 and MedPore. The human cartilage produced by this invention is useful in the treatment of cartilage deficiencies in the field of reconstructive surgery.

Kuala Lumpur Kuala Lumpur

ID : tm289599930


Construction of Tissue-engineered Bone Using Ceramic Scaffold and Fibrin

This invention provides a composite and method for regenerating (generating) bone tissues which have the mechanical strength suitable for use in implantation. The tissue-engineered bone construct is generated by seeding osteoprogenitors cells having the ability for osteoblast differentiation with fibrin as cell carrier onto a porous ceramic which serves as a scaffold for the cells. This invention also relates to the use of such composite in bone repair and replacement

Kuala Lumpur Kuala Lumpur

ID : tm289609931


Construction of Non-weight bearing Tissue-Engineered Bone

The invention provides a composition and method for the reconstruction of various shape of cartilages by using high density polyethylene as the endoskeleton material to provide predetermine, permanent shape and size of the cartilage graft. In the preferred embodiment, the cultured chondrocytes are mixed with autologous plasma derivative fibrin to form a three-dimensional neocartilage sheet. This was followed by incorporation of the neocartilage sheet with high density polyethylene which are trimmed into the desire shape. The formed autograft can be used for implantation. The tissue engineered cartilages in the invention are very useful for head and neck reconstructive surgery

Kuala Lumpur Kuala Lumpur

ID : tm289619932


Biopolymer Coating Composition

The coating composition comprises bacterial cellulose, plasticizer and pharmaceutically acceptable solvent. The method of preparing bacterial cellulose dispersion for making tablet coating film includes purifying the bacterial cellulose; milling the purified bacterial cellulose into powder form; sieving the powder; mixing the sieved powder into a pharmaceutically acceptable solvent; and homogenizing the mixture to form dispersion as coating composition.

Kuala Lumpur Kuala Lumpur

ID : tm289629933


An Improved Temporal Bone Holder

The improved temporal bone holder comprises an upper bowl-like vessel portion adapted with elongate retainer means, a drainage hole, and an external water supply means, and a substantially heavy base portion. Both the vessel and the base of the holder are inter-connected by an intermediate stem portion. The bottom end of said stem portion forms part of a pivotal means. The improved holder is made substantially of plastic material or aluminium alloy.

Kuala Lumpur Kuala Lumpur

ID : tm289639934


An Improved Swivel Arm Mechanism For Ear, Nose and Throat Operation

The invention relates to an improved swivel arm mechanism for ear, nose and throat operations. The embodiment of the invention comprises an anchoring means which is secured to the side of an operating table, a first adjusting means, which interconnects flexibly the anchoring means and an adjacent elongated arm portion, at least one elongated arm portion, another adjusting means, which interconnects flexibly an adjacent elongated arm portion and holder means, and a holder means, which accommodated an ear, nose and throat instruments, is characterized in which three adjusting means are being used to interconnect two elongated arm portions.

Kuala Lumpur Kuala Lumpur

ID : tm289649935


An Improve Temporal Bone Holder

The improved temporal bone holder comprises an upper bowl-like vessel portion adapted with elongate retainer means, a drainage hole, and an external water supply means, and a substantially heavy base portion. Both the vessel and the base of the holder are inter-connected by an intermediate stem portion. The bottom end of said stem portion forms part of a pivotal means. The improved holder is made substantially of plastic material or aluminium alloy.

Kuala Lumpur Kuala Lumpur

ID : tm289659936


A Method for Detecting Antibiotic-Associated Diarrhoea and Test Kit Thereof

This invention relates to a modified enzyme-linked immunoassay (ELISA) devised to detect the presence of C.difficile toxins in the fecal specimens of diarrhoea patients

Kuala Lumpur Kuala Lumpur

ID : tm289669937


A Culture Medium and Method for Culturing Chondrocytes

The invention provides an improved culture medium and method for expanding cells for use in tissue engineering and cartilage repair. The culture medium according to the present invention promotes 4 times higher chondrocyte growth rate; supports higher cell viability and shorter doubling time; provides 15 times larger amount of chondrocytes compared to the conventional medium. In tissue engineering, the culture chondrocytes from formulated medium demonstrates higher quality in morphological appearance, histological analysis and one step RT-PCR evaluation.

Kuala Lumpur Kuala Lumpur

ID : tm2922010191


A Needle Guide for Ultrasound Probe

Details on the invention:
Comprises a mechanism to affix the needle guide to an ultrasound probe
? A level guide with a positioning mechanism which level guide is attached to the front of the needle guide
? A guide wheel with gauges for various sizes of biopsy needles which guide wheel is attached to the body of the needle guide
. The biopsy needle is inserted through the guide wheel and the level guide and has a free

Kuala Lumpur Kuala Lumpur

ID : tm2922910200


Wear Testing Machine

The ability to resist friction is an important trait for materials used in dentistry. This machine was designed to test the wear of dental restorative materials such as amalgam, composite or glass ionomer cement. It may also be used to test the wear of other materials similar in nature

Kuala Lumpur Kuala Lumpur

ID : tm2923810209


Universal Endoscope Holder Cum Forearm Support System : An Ergonomic Assistive Innovation In Otolaryngologic Surgery

Operating over long-hours in unnatural body position put the surgeon's muscles, ligaments, and joints into strains which can be cumulative and potentially harmful. Shoulder Impingement Syndrome (SIS) and long head of bicep strain are some of the disorders resulted from this phenome. Affected surgeons may need to undergo specialized treatment (e.g., short-wave diathermy, intermittent pulse therapy, Sonotron, ultrasound, etc.,) and targeted exercise program like shoulder-scapular mobilization and muscles strengthening exercise.

We've made an innovative assistive support system to overcome these issues. It is a standalone platform which is not attached to the operating table or surgeon's chair. It has several articulated joint and telescopic mechanisms which can be set to the most comfortable working angle. By this way, the strain to the shoulder and the arm can be reduced tremendously, thus avoiding muscle fatigue and body ache.

This is an intuitive innovation for endoscopic-assisted otolaryngology surgery specially suited for the voice box and throat region. It is is incorporated to an adjustable portable arm rest for support which would be very helpful in the prevention of shoulder and elbow strain in long hour's surgery.

Kuala Lumpur Kuala Lumpur

ID : tm2924210213


Triaquora Rinse-Alcohol Free Plant - Based Oral Health Care Product

The oral health care product that we are formulating is a mixture of crude extracts of selected plants and is intended for use in the maintenance of oral hygiene. The product is in the form of mouth rinse. It is expected that the rinse will exhibit potential anti plaque effect and is a natural preservative

Kuala Lumpur Kuala Lumpur

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